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Modification

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Hybio is a hi-tech enterprise specialized in the R&D and manufacturing of diverse peptide products. Founder...

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Common Peptide Modifications
N-acetylation C-amidation
Benzyloxycarbonylation (N-Terminal) Biotin(N, C terminal and Side chain)
Phosphorylation-Serine Phosphorylation-Tyrosine
Phosphorylation-Threonine Chenodeoxycholic acid (N-Terminal)
Formylation (N-Terminal) Dansylation
Cyclization 
Disulfide bridge -one
Disulfide bridges -two
Disulfide bridges -three
intermolecular Disulfide bridge
thioester bond cyclic peptide
Amide cyclic (head to tail, side chain to tail , head to side chain , Asp to Lys, Glu to Lys)
Palmytolic acid (N-Terminal)
Succinylation Myristic acid (N-Terminal)
Fatty acid (N-Terminal) Thioglycollic acid (N-Terminal)
Acryl (N-Terminal) D(+)Glucose (N-Terminal)
Glu(NHC14H29)2 (C terminal) methyl ester (C terminal)
Guanidine (C terminal) Ethylamine (C terminal)
Methylamine (C terminal) PEGylation
Peptide Aldehyde Glycosylation (Thr, Ser)
Flourescence Dye Labeling
Tetramethylrhodamine、5(6)-TAMRA Fluorescein
FITC Carboxy Fluoresein
FAM (5-FAM, 6-FAM, 5(6)-FAM) Dansyl
Texas red N-terminal  
Peptide Conjugation  to  Carrie  Protein
KLH BSA
OVA  
Others  
MCA (N-Terminal) p-Nitroanilide(pNA, C-Terminal)
AMCA (C-Terminal)  
Lys (Me) Lys (Me)2
Lys (Me)3 Reduced amide bond
Special Amino Acids and Side Chain Modification
D-form amino acids N-Methyl amino acid (Ala, Phe, Leu, Ile, Val, Gly, Met)
pGlu, Hyp , Orn, Abu, Aib, (D)1-Nal, (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa, D-βNal、Dpr, Harg Phosphorylation (Tyr, Ser, Thr), Tyr(PO3H2), Thr(PO3H2), Ser(PO3H2),
Lys(Me)2, Lys(Me), Lys(Me)3, Arg(Me2), Lys(Ac), Lys(Fmoc), Lys(Biotin) Lys(DNP), Lys(ivDde) Tyr(nitrated), Tyr(OEt)
Cys(Cam)  (carbamidomethylated) K(Acryl), K(Cbz)
Met(O), Ser(Ac)  
Glu(Biotin), Asp(Biotin), His(Biotin)
Thr(Biotin), Ser(Biotin), Tyr(Biotin)
Tyr(SO3H2)
HYNIC (N-Terminal)
Isotope-labeled amino acids(H2, C13, N15)  
Long Peptide
Up to 70 mer  
Peptide Library
Peptide Library Multiple Antigenic Peptide System
Asymmetric 4 branches Asymmetric 8 branches
Peptide Nucleic Acid
Custom Organic Synthesis

Copyright 2009-2010 Hybio Pharmaceutical Co., Ltd.
Add: No.37, Keji C.2nd Hybio Medicine Park
Tel: +86-755-26588037   Fax: +86-755-26588022   E-mail:Janeli@hybio.com.cn
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